Risks associated with red blood cell transfusions: potential benefits from application of pathogen inactivation
نویسندگان
چکیده
منابع مشابه
Risks associated with fresh whole blood and red blood cell transfusions in a combat support hospital.
OBJECTIVE Fresh whole blood (FWB) and red blood cells (RBCs) are transfused to injured casualties in combat support hospitals. We evaluated the risks of FWB and RBCs transfused to combat-related casualties. DESIGN Retrospective chart review. SETTING Deployed U.S. Army combat support hospitals. SUBJECTS Donors of FWB and recipients of FWB and RBCs. MEASUREMENTS AND RESULTS The storage ag...
متن کاملCosts of outpatient red blood cell transfusions.
W ith the goals of improving oxygen delivery,1 reducing anemia, and enhancing quality of life, over 12 million red blood cell (RBC) units are transfused annually in the United States.2 At a hospital acquisition cost per RBC unit of $122 (1999 dollars),2 US acquisition costs exceed $1.5 billion annually. Adding testing and transfusion, the total health system cost for two units (based on prior s...
متن کاملRed blood cell transfusions in acute paediatrics.
Red blood cell (RBC) transfusions should usually be given only to restore or maintain oxygen delivery to vital organs and tissues. Medical history has clearly documented the importance of blood transfusion in saving lives threatened by acute haemorrhage or severe anaemia. The availability of blood products has facilitated many surgical and medical advances, allowing the support of patients who ...
متن کاملPlatelet transfusions: trigger, dose, benefits, and risks
Over the last half century, platelet transfusion has been an effective therapy for the prevention and treatment of bleeding, particularly in patients with hematologic malignancies. Recent randomized trials have demonstrated that current practices may be suboptimal in a number of ways. The rationale for parsimony in the use of this powerful therapy includes previously described severe and fatal ...
متن کاملRed-blood-cell alloimmunization and number of red-blood-cell transfusions.
BACKGROUND Patients receiving red-blood-cells may form antibodies against the alloantigens expressed by red-blood-cells, with the risk of serious morbidity and the need for extensive phenotype-matching in subsequent transfusions. The incidence of alloimmunization is considered variable for specific patient groups and for first time antibody formation. We therefore studied the cumulative inciden...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2015
ISSN: 0041-1132,1537-2995
DOI: 10.1111/trf.13259